Deffo turn VR off, if you need it on a tripod shot it means your tripod is rubbish & not up to the job, you need a Gitzo LOL On a more serious note the way VR works in lenses is it goes in the opposite direction to the shake, they are also very very fragile, being held in place by 4 small plastic pegs, we have a Canon one in our workshop that had gone by just putting the lens down a bit to heavy, our engineer loves them as they snap so easy & cost a fortune to replace so always treat you VR lens with kids gloves to avoid having to empty your wallets.
We have had loads of trouble with VR lenses & a Canon 100-400 was giving double images when used at slower speeds due to the VR still operating when exposing, the cure, turn it off & remove filter, images were then sharper & double image free, to much reliance on modern technology we do not really need, I try to avoid VR lenses like the plague if I can myself, I have one as a kit lens but it is turned off all the time.
Just my little contribution & own opinion.
Andy